Published on: April 19, 2024

MACACINE HERPESVIRUS 1 (MCHV-1)

MACACINE HERPESVIRUS 1 (MCHV-1)

NEWS – A 37-year-old man wounded by a wild monkey in Hong Kong is in intensive care suffering from infection with B virus.

HIGHLIGHTS

  • Nature of the Virus:
    • B virus is enzootic in macaques of the genus Macaca and is the only identified old-world-monkey herpesvirus.
    • While asymptomatic in macaques, it can cause severe neurological complications, such as encephalitis.
  • Transmission:
    • In humans, B virus is transmitted through bites, scratches, or contact with infected bodily fluids from macaque monkeys.
    • Human-to-human transmission of this virus is rare, with only one recorded case so far.
  • Symptoms in Humans:
    • B virus infections in humans are rare but can be fatal, presenting symptoms ranging from fever and headache to neurological dysfunction and even death.
    • Common symptoms include fever, headache, myalgia, and localized neurologic symptoms near the wound site.
    • Signs of infection typically appear within two to 30 days, often accompanied by blisters around the contact point or wound, resembling a flu-like illness.
    • The virus can spread to lymph nodes and the nervous system, leading to agitation, confusion, double vision, coordination issues, muscle weakness, and hiccups if inflammation affects the brain stem.
  • Treatment:
    • Currently, there are no vaccines available to protect humans against B virus infection.
    • Treatment primarily focuses on managing symptoms and complications, with severe cases requiring intensive care and supportive measures.